An automated caffeine-guidance algorithm determines caffeine dosage and ideal timings



A new study has discovered a web-based caffeine optimization tool to keep a check on caffeine intake by developing effective strategies. The team of researchers created a caffeine consumption guidance, this they made possible through an open-access tool called 2B-Alert Web 2.0. The results were then compared to U.S. Army guidelines.

The results through the optimization tool suggested that an average 40% less caffeine or an additional 40% was required. Caffeine is the most popular stimulant was used to steer away sleep and induce alertness. The study encourages the right amount of caffeine at the right time. “Our 2B-Alert Web tool allows an individual, in our case our service members, to optimize the beneficial effects of caffeine while minimizing its consumption,” reports Jaques Reifman, Ph.D., at the Department of the Army Senior Research Scientist for Advanced Medical Technology. Reifman is also the head investigator and an Army Senior Research Scientist for Advanced Medical Technology, serving at the U.S. Army Medical Research and Development Command at Ft. Detrick, Maryland.

According to reports, Reifman compared algorithm with caffeine dosing strategies of four studies from previously published works of experimental studies. By introducing an automated caffeine-guidance algorithm the team extended their former work in the subject area. The algorithm can be incorporated in an open-access tool to provide users with several inputs like the minimum desirable level of alertness, the desirable peak-alertness periods within a sleep/wake schedule, and maximum tolerable daily caffeine intake.

As a consequence, 2B-Alert Web 2.0 tool can predict alertness of average individual as well as the person’s caffeine and sleep/wake schedule. The tool is also capable of making users acquire optimal caffeine timing and provides doses to achieve peak alertness at desired times.

An abstract of the research was published in the journal Sleep. The research will be presented on June 12 at the 33rd annual meeting of the Associated Professional Sleep Societies LLC (APSS). The tool is freely available and the team reports that its practical use will be helpful in the realms of military and also in the research lab.

“For example, if you pull an all-nighter, need to be at peak alertness between, say, 9 a.m. and 5 p.m., and desire to consume as little caffeine as possible, when and how much caffeine should you consume?” Reifman said. “This is the type of question 2B-Alert was designed to answer.”